COMPOSITIONS ET PROCEDES DE TRAITEMENT DE TROUBLES DU METABOLISME DES ACIDES GRAS

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专利权人:

THE CHILDREN'S HOSPITAL OF PHILADELPHIA

发明人:

ISCHIROPOULOS, HARRY,DOULIAS, PASCHALIS-THOMAS

申请号：

CA2919671

公开号：

CA2919671A1

申请日:

2014.07.29

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

Compositions and methods for inhibiting, treating, and/or preventing fatty acid metabolism disorders, particularly fatty acid oxidation disorders, in a subject are provided. The method comprises administering at least one S-nitrosylating agent to the subject. In a particular embodiment, the fatty acid oxidation disorder is very long-chain acyl-coenzyme A dehydrogenase deficiency (VLCADD). In a particular embodiment, the S-nitrosylating agent is S-nitroso-Nacetyl-cysteine (SNO-NAC).

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