MACDONALD, LYNN,MURPHY, ANDREW J.,MCWHIRTER, JOHN,TU, NAXIN,VORONINA, VERA,GURER, CAGAN,MEAGHER, KAROLINA,STEVENS, SEAN
申请号:
PL12784833
公开号:
PL2771357T3
申请日:
2012.10.26
申请国别(地区):
PL
年份:
2018
代理人:
摘要:
The invention provides a genetically modified non-human animal that comprises in its genome unarranged T cell receptor gene loci, as well as non-human embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified non-human animal and methods of making the same. Various methods of using the genetically modified non-human animal are also provided.