CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
发明人:
MEIJER, LAURENT,SKALTSOUNIS, LEANDROS,MIKROS, EMMANUEL,MAGIATIS, PROKOPIOS,JOHNSON, CARL
申请号:
AT09802595
公开号:
AT547401T
申请日:
2009.07.21
申请国别(地区):
AT
年份:
2012
代理人:
摘要:
Indirubin derivatives of formula I wherein R represents -(A) n - R 1 or -CO-N(R 2 ,R 3 ) with €¢ A being C1-C5 alkylene group, optionally substituted by one or several A 1 radical, A 1 being an halogen Br, OH, OR 4 or NH 2 , R 4 being C1-C5 alkyl; €¢ R 1 being halogen, OH, N(R 2 , R 3 ); R 2 and R 3 , identical or different, being C1-C5 alkyl, optionally substituted by A 1 such as above defined, or R 2 and R 3 are part of a cycle with 5 or 6 elements optionally comprising another heteroatom such as O or N; €¢ n = 1-5. It also relates to the biological application thereof.