The purpose of the present invention is to provide a composition for inhibiting the migration of endotoxin into blood. According to the present invention, a composition for inhibiting the migration of endotoxin into blood is provided, which contains a whey protein. The whey protein can be selected from the group consisting of [alpha]-lactalbumin, [beta]-lactoglobulin and lactoferrin. The composition according to the present invention may additionally contain a fermented milk protein.本發明係以提供一種抑制內毒素之血中移行的組成物為目的。根據本發明,可提供一種包含乳清蛋白質而成的內毒素之血中移行抑制用組成物。乳清蛋白質可選自由α-乳白蛋白、β-乳球蛋白及乳鐵蛋白所成群組。本發明之組成物亦可進一步包含發酵乳蛋白質。