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METHOD FOR ACTIVATION OF HELPER T CELL AND COMPOSITION FOR USE IN THE METHOD
专利权人:
INC.;INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY
发明人:
SUGIYAMA, HARUO
申请号:
NZ59916008
公开号:
NZ599160A
申请日:
2008.02.27
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Provided is the use of a WT1 peptide, a polynucleotide encoding said peptide, an expression vector comprising said polynucleotide, or a cell including said expression vector in the manufacture of a medicament for the treatment or prevention of cancer in a subject who is HLA-DPB1*0901 positive, wherein said WT1 peptide has the ability to bind to HLA-DPB1*0901, and is a peptide selected from: (1) a peptide comprising the amino acid sequence Lys Arg Tyr Phe Lys Leu Ser His Leu Gln Met His Ser Arg Lys His ; or (2) a peptide of (1), wherein the amino acid sequence has a substitution, modification or deletion of one to several amino acids.
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