תרכובות הדומות לציקלופאמין ותכשירי רוקחות אנטי–סרטניים המכילים אותן

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专利权人:

INFINITY DISCOVERY INC.

发明人:

申请号：

IL18130107

公开号：

IL181301A

申请日:

2007.02.13

申请国别(地区):

IL

年份:

2015

代理人:

摘要：

The present invention provides a preparation method for analogs of cyclopamine of formula 1 that can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, Ptc loss-of-function or smoothened gain-of-function mutations. The compounds of the present invention are particularly useful in treating cancers.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/