patent summary: "substituted benzamide derivatives". The present invention relates to compounds of formula I wherein R1 is hydrogen, halogen, cyano, lower alkyl, halogen substituted lower alkyl, lower alkoxy, halogen substituted lower alkoxy or C (o) nh2, or is optionally substituted phenyl halogen-substituted halogen, cyano or lower alkoxy is either 2,2-difluorobenzo [d] [1,3] dioxol-5-yl, or is 6- (trifluoromethyl) pyrazin-2-yl or 5- (trifluoromethyl) pyrazin-2-yl is either 6- (trifluoromethyl) pyrimidin-4-yl, or is 6- (trifluoromethyl) pyridin-3-yl, or is 5-cyanopyrazin-2-yl or is 2- (trifluoromethyl) pyrimidin-4 -ila； n is 1 or 2 r2 is halogen, lower alkyl or cyano and r3 is hydrogen, or r2 is hydrogen and r3 is halogen, lower alkyl or cyano； x is a bond, -nr'-, -ch2nh- or -chr'-； R 'is hydrogen or lower alkyl； z is a bond, -ch2- or -o-； ar is phenyl or heteroaryl, selected from the group consisting of 1h-indazol-3yl, pyridin-2-yl, pyridin-3-yl, pyridin-4-yl, pyrimidin-5-yl, 1h-pyrazol-3-one yl, 1h-pyrazol-4-yl or 1h-pyrazol-5-yl； or a pharmaceutically suitable acid addition salt thereof, which may be used in the treatment of depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder (ADHD), stress-related disorders, psychotic disorders, schizophrenia, neurological diseases, parkinson's disease, neurodegenerative disorders, alzheimer's disease, epilepsy, migraine, hypertension, drug abuse, metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, energy consumption and assimilation disorders, diseases and malfunction of body temperature homeostasis, sleep and circadian rhythm disorders, and cardiovascular disorders.resumo patente de invenção: "derivados de benzamida substituídas". a presente invenção refere-se aos compostos de fórmula i em que r1 é hidrogênio, halogênio, ciano, alquila inferior, alquila inferior substituída por halogênio, alcóxi inferior, alcóxi inferior substituído por halogên
