Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof

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专利权人:

AEterna Zentaris GmbH

发明人:

Gunther, Eckhard,Schaefer, Olaf,Teifel, Michael,Paulini, Klaus

申请号：

AU2007293650

公开号：

AU2007293650B2

申请日:

2007.09.06

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The present invention provides conjugates of disorazoles and their derivatives with cell-binding molecules, such as peptides, proteins, hormones, blood proteins and anti-bodies. The present invention further provides novel disorazole derivatives and processes of manufacturing such conjugates and disorazole derivatives. These compounds can be used as medicaments for the treatment of physiological and/or pathophysiological conditions in mammals, in particular for the treatment of various tumors.

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中国工程科技知识中心

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