CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF

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专利权人:

AEterna Zentaris GmbH

发明人:

GUNTHER Eckhard,GUNTHER Eckhard,SCHAEFER Olaf,SCHAEFER Olaf,TEIFEL Michael,TEIFEL Michael,PAULINI Klaus,PAULINI Klaus

申请号：

SI200731775

公开号：

SI2066679T1

申请日:

2007.09.06

申请国别(地区):

SI

年份:

2016

代理人:

摘要：

The present invention provides conjugates of disorazoles and their derivatives with cell-binding molecules, such as peptides, proteins, hormones, blood proteins and antibodies. The present invention further provides novel disorazole derivatives and processes of manufacturing such conjugates and disorazole derivatives. These compounds can be used as medicaments for the treatment of physiological and/or pathophysiological conditions in mammals, in particular for the treatment of various tumors.

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中国工程科技知识中心

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http://www.ckcest.cn/home/