IOVANCE BIOTHERAPEUTICS, INC.;WARDELL, Seth;BENDER, James;LOTZE, Michael, T.
发明人:
WARDELL, Seth,BENDER, James,LOTZE, Michael
申请号：
WO2018US12633
公开号：
WO2018182817(A1)
申请日:
2018.01.05
申请国别(地区):
世界知识产权组织国际局
年份:
2018
代理人:
摘要：
The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
