Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

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专利权人:

IOVANCE BIOTHERAPEUTICS, INC.

发明人:

Wardell Seth,Bender James,Lotze Michael T.

申请号：

US201815892311

公开号：

US10130659(B2)

申请日:

2018.02.08

申请国别(地区):

美国

年份:

2018

代理人:

Morgan, Lewis & Bockius LLP

摘要：

The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/