BRESSLER, ERIC M.,GREEN, JORDAN J.,PANDEY, NIRANJAN B.,POPEL, ALEKSANDER S.,SHMUELI, RON B.
申请号：
CA3005284
公开号：
CA3005284A1
申请日:
2016.11.18
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention in various aspects and embodiments involves pharmaceutical compositions of peptides derived from the a5 fibril of type IV collagen, and uses thereof for medical treatment. The peptides target a5ß1 and a?ß3 integrins, and inhibit signaling through multiple receptors, and find use for inhibiting vascular permeability, angiogenesis, lymphangiogenesis.
