BRESSLER ERIC M,GREEN JORDAN J,PANDEY NIRANJAN B,POPEL ALEKSANDER S,SHMUELI RON B
申请号:
IN201817021119
公开号:
IN201817021119A
申请日:
2018.06.06
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present invention in various aspects and embodiments involves pharmaceutical compositions of peptides derived from α5 fibril of type IV collagen, and uses thereof for medical treatment. The peptides target α5β1 and ανβ3 integrins, and inhibit signaling through multiple receptors, and find use for inhibiting vascular permeability, angiogenesis, lymphangiogenesis.