Bressler, Eric M.,Green, Jordan J.,Pandey, Niranjan B.,Popel, Aleksander S.,Shmueli, Ron B.
申请号:
AU2016358125
公开号:
AU2016358125A1
申请日:
2016.11.18
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention in various aspects and embodiments involves pharmaceutical compositions of peptides derived from the α5 fibril of type IV collagen, and uses thereof for medical treatment. The peptides target α5β1 and ανβ3 integrins, and inhibit signaling through multiple receptors, and find use for inhibiting vascular permeability, angiogenesis, lymphangiogenesis.