The invention provides a single-needle integrated artificial pancreas. The single-needle integrated artificial pancreas comprises a medicine storage unit, a medicine application drive unit, an indwelling unit and a blood glucose monitoring and insulin application control unit, wherein the medicine application drive unit is connected with the medicine storage unit the indwelling unit is connected with the medicine storage unit and comprises a glucose sensor, an insulin indwelling hose, a puncture needle and an installation device assisted by the puncture needle, the glucose sensor and the insulin indwelling hose are implanted at the same part of subcutaneous tissue of a patient at the same time through the installation device the puncture needle is a steel puncture needle or a groove puncture needle the blood glucose monitoring and insulin application control unit is connected with the medicine storage unit, the medicine application drive unit and the indwelling unit respectively. According to the single-needle integrated artificial pancreas, the insulin indwelling hose and the glucose sensor in the artificial pancreas can be implanted at the same part of the subcutaneous tissue of the human body, and therefore the probability that diabetic patients are infected is lowered besides, the single-needle integrated artificial pancreas is easy to install and convenient to use.
