Disclosed is a single needle integrated artificial pancreas, wherein the single needle integrated artificial pancreas comprises a fluid reservoir unit a fluid driving unit connected to the drug reservoir unit an indwelling unit connected to the fluid reservoir unit and comprising a glucose sensor, an insulin indwelling cannula, a puncture needle and an inserter wherein the glucose sensor and the indwelling cannula are simultaneously implanted in the same subcutaneous tissue in a patient via the inserter under the aid of the puncture needle and the puncture needle is a steel puncture needle or groove puncture needle and a glucose monitoring and insulin delivery control unit is respectively connected to the fluid reservoir unit, the fluid driving unit and the indwelling unit. The single needle integrated artificial pancreas reduces the chance of a diabetic patient being infected and is simple in installation and convenient to use.
