Disclosed is a single needle integrated artificial pancreas, wherein the single needle integrated artificial pancreas comprises a drug reservoir unit (1) a dosing drive unit (2) connected to the drug reservoir unit (1) an indwelling unit (3) connected to the drug reservoir unit (1) and comprising a glucose sensor (31), an insulin-indwelling hose (32), a puncture needle (33) and an mounting means (34) wherein the glucose sensor (31) and the insulin-indwelling hose (32) are simultaneously implanted in the same subcutaneous tissue in a patient via the mounting means (34) under the aid of the puncture needle (33) and the puncture needle (33) is a steel puncture needle or groove puncture needle and a blood glucose monitoring and insulin administration controlling unit (4) is respectively connected to the drug reservoir unit (1), the dosing drive unit (2) and the indwelling unit (3). The single needle integrated artificial pancreas is able to simultaneously implant the insulin-indwelling hose (32) and the glucose sensor (31) of the artificial pancreas into the same site of a subcutaneous tissues in a patient, thus reducing the chance of a diabetic patient being infected and is simple in installation and convenient to use.
