An affected portion located at a position in the close vicinity of an inserted-portion main unit is treated while reducing interference with tissue or the like in the surrounding area. Provided is a treatment manipulator (2) including an inserted-portion main unit (7); at least one arm (8) that is provided so as to protrude forward from a distal-end surface of the inserted-portion main unit (7) and that has an end effector (8a) at the distal end thereof; and an endoscope (9) that is provided in the inserted-portion main unit (7) and that has a viewing-field area in which the end effector (8a) at the distal end of the arm (8) can be observed, wherein the arm (8) is provided with, sequentially from the distal-end side, a first flexing joint (11) that can pivot the end effector (8a) about a first axis orthogonal to a longitudinal axis of the arm (8), an intermediate roll joint (12) that can be rotated about the longitudinal axis, and a second flexing joint (13) that can be pivoted about a second axis orthogonal to the longitudinal axis, and the first flexing joint (11) can be flexed 90° or more, at least on one side, with respect to the longitudinal axis.