BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;INTEGRICO COMPOSITES, INC.
发明人:
BROUGH, CHRIS,MCGINITY, JAMES W.,MILLER, DAVE A.,DINUNZIO, JAMES C.,WILLIAMS, ROBERT O., III
申请号：
CA2697099
公开号：
CA2697099C
申请日:
2008.08.21
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Compositions and methods for making a pharmaceutical dosage form includemaking a pharmaceutical compositionthat includes one or more active pharmaceutical ingredients (API) with one ormore pharmaceutically acceptable excipients bythermokinetic compounding into a composite. Compositions and methods ofpreprocessing a composite comprising one or moreAPIs with one or more excipients include thermokinetic compounding, comprisingthermokinetic processing the APIs with theexcipients into a composite, wherein the composite can be further processed byconventional methods known in the art, such as hotmelt extrusion, melt granulation, compression molding, tablet compression,capsule filling, film-coating, or injection molding.
