Zuo Yongs And Qie Ke Fitness what is used to control Treatment Elixirs as the disease for being related to the refreshing The Zhang Hinder of Gu An Suan Which Machine Neng Zhang Hinder with what and being related to mGluR2 Ke receives Which as mGluR2 antidote on the compound representated by followingization Learn formula (I) or Qi Drug Learn, such as Ah Seoul's Ci Haimo disease: wherein R is Hydrogen atom, 6 alkyl of C1 or Class like object, R1 is 6 alkyl of C1,6 alkoxy of C1 or Class like object, R2 Shi Halogen element atom, 6 alkyl of C1,6 alkoxy of C1 or Class are like object, R3 is that perhaps Class is like Wu And and R4 is 6 alkyl of C1 or Class like object for Hydrogen atom, 6 alkyl of C1.由以下化學式(I)所代表的化合物或其藥學上可接受的鹽作爲mGluR2拮抗劑起作用並且可適用於作爲用於涉及谷氨酸鹽機能障礙的神經障礙以及涉及mGluR2的疾病的治療劑，例如阿爾茨海默病：其中R是氫原子、C1 6烷基或者類似物，R1是C1 6烷基、C1 6烷氧基或者類似物，R2是鹵素原子、C1 6烷基、C1 6烷氧基或者類似物，R3是氫原子、C1 6烷基或者類似物，並且R4是C1 6烷基或者類似物。
