NEW CLASS OF HISTONE DEACETYLASE INHIBITORS

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专利权人:

Saverio Minucci

发明人:

Saverio Minucci,Pier Giuseppe Pelicci,Antonello Mai,Marco Ballarini,Gaetano Gargiulo,Silvio Massa,Florian Thaler,Gilles Pain,Andrea Colombo,Stefania Gagliardi,Mario Varasi,Ciro Mercurio

申请号：

US13100670

公开号：

US20120115867A1

申请日:

2011.05.04

申请国别(地区):

US

年份:

2012

代理人:

摘要：

This invention is related to new histone deacetylase inhibitors according to the general formula (I) wherein: Q is a bond, CH2, NR5 or oxygen, X is CH or nitrogen, Y is a bond, CH2, oxygen or NR6, Z is CH or nitrogen, R1, R2 are, independently, hydrogen or C1-C6 alkyl, R3, R4 are, independently, hydrogen, halogen, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 haloalkyl or C1-C6 haloalkoxy, and R5 and R6 are as further defined in the specification, and pharmaceutical acceptable salts thereof.

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