Antonello Mai,Saverio Minucci,Florian Thaler,Gilles Pain,Andrea Colombo,Stefania Gagliardi,Pier Giuseppe Pelicci,Marco Ballarini,Gaetano Gargiulo,Silvio Massa
申请号:
US12962209
公开号:
US08242175B2
申请日:
2010.12.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
New histone deacetylase inhibitors according to the general formula (I)wherein: Q is a bond, CH2, CH—NR3R4, NR5 or oxygen, X is CH or nitrogen, Y is a bond, CH2, oxygen or NR6, Z is CH or nitrogen, R1, R2 are, independently, hydrogen, halogen, C1-C6 alkyl or C1-C6 haloalkyl, R11, R12 are, independently, hydrogen or C1-C6 alkyl, and R3, R4, R5 and R6 are as further defined in the specification.