PROBLEM TO BE SOLVED: To provide functional foods, medical products and the like which can effectively alleviate allergic symptoms of a human and the like and which are safe and secure even if using as an oral agent.SOLUTION: Functional foods, medical products and the like which contain as an active ingredient the supernate fluid obtained by protease treatment of grind dust of dried small sardine having abundant food experiences, or a dried material thereof can be safely used as an oral agent to a human and the like, and allergic symptoms can be effectively alleviated by effects such as basophil degranulation inhibition and cytokine production-promoting of macrophages.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】ヒトなどのアレルギー症状を効果的に緩和させることが可能な、経口用剤として用いても安全、安心な機能性食品、医薬品等を提供する。【解決手段】食経験が豊富な煮干し粉砕品をプロテアーゼで処理した上清液又はその乾燥物等を有効成分とする機能性食品、医薬品等により、ヒトなどが経口用剤として安心して用いることが可能であり、且つ、好塩基球の脱顆粒抑制やマクロファージのサイトカイン産生促進などの作用によってアレルギー症状を効果的に緩和することができる。【選択図】なし
