The compounds according to formula (1) are pharmacologically effective as inhibitors of Potassium Channel Inhibitors, in particular of the current of the inward Rectifier Potassium Channel operated by acetylcholine (i.e. ikach blockers) and are believed to be useful in the tra Treatment of Cardiac arrhythmias, including supraventricular tachyarrhythmias.Such as atrial fibrillation and atrial flutter.Claim 1: a compound having the structure of formula (1) or a pharmaceutically acceptable Salt thereof, wherein each Optional R5 is selected regardless of fluoro, Nitrile, Hydroxy, oxo c1-5 alkyl, cycloalkyl, c3-5, alkoxy or alkoxyalkyl Esters C1 C1 - 5 - 5, where any R is alkyl group, alkoxy or cycloalkyl substituted by 0,1 or 2 fluoro substituents are selected independently, or Hydroxy Nitrile； r1 is selected from C1 - C3 6 alkyl, cycloalkyl or alkoxyalkyl Esters C1 - 6 - 6, where any alkyl group, alkoxy substituted cycloalkyl or is 0, 1 or 2 substituents are selected independently Tea Fluorine or Nitrile； R2 is selected from Hydrogen, alkyl or c1-3； R3 is selected from alkyl C1 - 6Cycloalkyl or alkoxyalkyl Esters C1 C3 - 6 - 6, where any alkyl or cycloalkyl Group in these substituents is replaced by 0, 1 or 2 fluoro substituents are selected independently, or Hydroxy Nitrile； each R4 Optional is selected regardless of Halo, Hydroxy Nitrile C1-3 alkyl, alkoxy, c1-3, c1-3 alkyl or alkoxyalkyl Esters 3sulfuro C1 -,Where any Group alkyl or alkoxy substituents in these is replaced by 0, 1, 2 or 3 of Halo substituents are selected independently, or Hydroxy Nitrile； M is selected from 1, 2 or 3； Selects n is 1 or 2； X is selected from 0, 1, 2 or 3； and select 0, 1, 2 Or 3.Los compuestos de acuerdo con la fórmula (1) son farmacológicamente efectivos como inhibidores del canal de potasio, en particular inhibidores de la corriente del canal de potasio rectificador de entrada operada por acetilcolina (es decir bloqueadores de IKACh) y se cree que son útiles en el tratamiento de a
