PROBLEM TO BE SOLVED: To provide a composition having a preventing, improving and/or treating effect for diabetes mellitus.SOLUTION: There are provided a pharmaceutical composition containing the extract of Jerusalem artichoke fermented by genus Lactobacillus sp. as an active constituent for preventing and treating diabetes mellitus and a health food composition. The composition has remarkably excellent anti-diabetes mellitus effect compared to that of the extract of Jerusalem artichoke which has not been fermented.COPYRIGHT: (C)2013,JPO&INPIT【課題】糖尿病の予防、改善及び/または治療効果を有する組成物の提供。【解決手段】ラクトバシルス属微生物で発酵させた菊芋発酵抽出物を有効成分として含む糖尿病の予防及び治療用薬学組成物および健康食品組成物。該組成物は発酵させていない菊芋抽出物よりも抗糖尿効果がはるかに優れている。【選択図】図6