BOEHRINGER INGELHEIM INTERNATIONAL GMBH;VITAE PHARMACEUTICALS INC
发明人:
ECKHARDT MATTHIAS,NAR HERBERT,HIMMELSBACH FRANK
申请号：
AP201206248
公开号：
AP201206248A0
申请日:
2010.11.05
申请国别(地区):
AP
年份:
2012
代理人:
摘要：
The present invention relates to compounds defined by formula I wherein the variables R1, R2, R3, R4, and m are defined as in claim 1, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of 11beta-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity, and dyslipidemia.
