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aryl and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline
专利权人:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
发明人:
BING-SHIOU YANG,HANS-JUERGEN MARTIN,MARTIN SCHUEHLE,MATTHIAS ECKHARDT,SANDRA SICK
申请号:
BR112013011095
公开号:
BR112013011095A2
申请日:
2011.11.04
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present invention relates to compounds defined by formula I wherein the variables R1, R2, R3, R4, and m are defined as in claim 1, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of 11&bgr;-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity, and dyslipidemia.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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