The invention relates to a method for inducing a protection against the 4 dengueserotypes in a patient, that comprises: (a) a first series of administrations(i) of a dose of a dengue vaccinal virus of a first serotype and a dose of a denguevaccinal virus of a second serotype, and (ii) of a dose of a dengue vaccinal virusof a third serotype and a dose of a dengue vaccinal virus of a fourth serotype, and(b) a second series of administrations of the (i) and (ii) doses, wherein the (i)and (ii) doses are administered simultaneously at separate anatomical sitesand wherein the second series is administered at least 30 days and at most 12 monthsafter the first series.
