The invention relates to a method of inducing homologous protection against the four serotypes of dengue in a patient, comprising the sequential administration in said patient (i) of a dose of a vaccinal virus of the dengue of a first serotype and a dose of a vaccinal virus of a second serotype, and (ii) a dose of a vaccinal virus of the dengue of a third serotype and a dose of a vaccinal virus of the dengue of a fourth serotype, in which the vaccinal viruses of the dengue (ii) are administered at least 30 days and no more than 1 year after the administration of the vaccinal viruses (i).
