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SYSTEM AND METHOD FOR CHARACTERIZATION OF A BRAIN TISSUE SAMPLE USING RAMAN MARKER REGIONS
专利权人:
HENRY FORD HEALTH SYSTEM;WAYNE STATE UNIVERSITY
发明人:
Gregory William AUNER,Michelle BRUSATORI,Steven N. KALKANIS,Lisa SCARPACE
申请号:
US16605926
公开号:
US20200138293A1
申请日:
2018.04.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A system for characterization of a brain tissue sample includes a laser having an excitation fiber and a probe coupled to the excitation fiber for irradiating the brain tissue sample with light at an excitation wavelength. The probe further includes a plurality of return fibers for receiving light scattered from the brain tissue sample, wherein each return fiber includes a microfilter that permits light to pass for a different, spaced apart marker region. A Raman spectrometer is in communication with the plurality of return fibers, and a processor is in communication with the Raman spectrometer for analyzing Raman spectra within the marker regions to identify a tissue type of the brain tissue sample as one of normal white matter brain tissue, normal grey matter brain tissue, brain tumor tissue, infiltrating tumor tissue, and necrotic tissue.
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