The Board of Regents of The University of Texas System
发明人:
SIEGWART, Daniel J.,HAO, Jing,ZHOU, Kejin,MILLER, Jason,KOS, Petra,XUE, Lian
申请号:
EP15866947
公开号:
EP3229842A4
申请日:
2015.12.08
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Polymers produced by ring opening polymerization which comprises an amino group that can be used in compositions to deliver a nucleic acid such as a miRNA or a siRNA. In some embodiments, compositions which comprise the polymers described herein and a nucleic acid are also provided herein. In some embodiments, these compositions are used to silence one or more genes in vivo or treat a disease or disorder.