The Government of the United States of America as Reprisented by Secretary of the Army
发明人:
Carl R. ALVING,Jerome H. KIM,Mangala RAO
申请号：
US15127076
公开号：
US20170165358A1
申请日:
2014.07.09
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Provided herein are (1) a method of mixing an aluminum salt-adsorbed immunogen with a monophosphoryl lipid A (MPLA)-containing liposome (L(MPLA)), and (2) the resulting immunogenic composition. The resulting immunogenic composition has an enhanced immunostimulation potency compared with either a composition comprising the uncapsulated immunogen mixed with the L(MPLA) or the aluminum salt-adsorbed immunogen alone.
