METHODS FOR ENHANCING THE IMMUNOSTIMULATION POTENCY OF ALUMINUM SALT ADSORBED VACCINES

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专利权人:

发明人:

ALVING CARL R,KIM JEROME H,RAO MANGALA

申请号：

IN201647034809

公开号：

IN201647034809A

申请日:

2016.10.12

申请国别(地区):

IN

年份:

2016

代理人:

摘要：

Provided herein are (1) a method of mixing an aluminum salt adsorbed immunogen with a monophosphoryl lipid A (MPLA) containing liposome (L(MPLA)) and (2) the resulting immunogenic composition. The resulting immunogenic composition has an enhanced immunostimulation potency compared with either a composition comprising the uncapsulated immunogen mixed with the L(MPLA) or the aluminum salt adsorbed immunogen alone.

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