Biemans, Barbara,Guba, Wolfgang,Jaeschke, Georg,Ricci, Antonio,Rueher, Daniel,Vieira, Eric
申请号：
UAA201608260
公开号：
UA119053C2
申请日:
2015.01.07
申请国别(地区):
UA
年份:
2019
代理人:
摘要：
The present invention relates to compounds of formula (I) wherein Y is C-R1； R' is hydrogen or halogen； R1 is hydrogen or halogen； R2 is hydrogen, lower alkyl or phenyl,； R4 is hydrogen or lower alkyl； or R2 and R4 may form together with the corresponding atoms, to which they are attached the following rings: (A), (B), (C), (D) or (E)； R5 is hydrogen or lower alkyl； and if R2 and R4 form a ring as described above, than R5 is hydrogen； or R4 and R5 may form together with the C-atom to which they arc attached a heterocycloalkyl ring； R3 is phenyl or pyridinyl, wherein the N atom in the pyridinyl group may be in different positions； or to a pharmaceutically acceptable salt or acid addition salt, to a racemic mixture, or to its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof. The compounds may be used for the treatment of Parkinson's disease, anxiety, emesis, obsessive compulsive disorder, autism, neuroprotection, cancer, depression and diabetes type 2. (I)Винахід стосується сполук формули І, які застосовують для лікування хвороби Паркінсона, тривожного розладу, нудоти і блювоти, обсесивно-компульсивного розладу, аутизму, при нейропротекції, лікуванні онкологічного захворювання, депресивного синдрому і діабету 2 типу. (I)
