FORMULATION A LIBERATION IMMEDIATE DE 4-METHYL-3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]-N-[5-(4-METHYL- 1H-IMIDAZOL-1-YL)-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE

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专利权人:

NOVARTIS AG

发明人:

BHARDWAJ, UPKAR,BORDAWEKAR, MANGESH SADASHIV,COMFORT, ANN REESE,LI, PING,LI, SHOUFENG,MAKAROV, ALEXEY

申请号：

CA2855503

公开号：

CA2855503A1

申请日:

2012.11.12

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

A solid dosage form of nilotinib is disclosed that comprises: (i) a core comprising 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide or a pharmaceutically acceptable salt thereof and excipients； and (ii) at least one polymer, said polymer coating said core, wherein disintegration of said solid dosage form is delayed.

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