BHARDWAJ, UPKAR,BORDAWEKAR, MANGESH SADASHIV,COMFORT, ANN REESE,LI, PING,LI, SHOUFENG,MAKAROV, ALEXEY
申请号:
SG11201401476T
公开号:
SG11201401476TA
申请日:
2012.11.12
申请国别(地区):
SG
年份:
2014
代理人:
摘要:
A solid dosage form of nilotinib is disclosed that comprises: (i) a core comprising 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide or a pharmaceutically acceptable salt thereof and excipients; and (ii) at least one polymer, said polymer coating said core, wherein disintegration of said solid dosage form is delayed.