BHARDWAJ UPKAR,BORDAWEKAR MANGESH SADASHIV,COMFORT ANN REESE,LI PING,LI SHOUFENG,MAKAROV ALEXEY
申请号:
TN2014000177
公开号:
TN2014000177A1
申请日:
2014.04.25
申请国别(地区):
TN
年份:
2015
代理人:
摘要:
A solid dosage form of nilotinib is disclosed that comprises: (i) a core comprising 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide or a pharmaceutically acceptable salt thereof and excipients; and (ii) at least one polymer, said polymer coating said core, wherein disintegration of said solid dosage form is delayed.