IMMEDIATE RELEASE 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide FORMULATION

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专利权人:

Upkar Bhardwaj

发明人:

Upkar Bhardwaj,Ann Reese Comfort,Ping Li,Shoufeng Li,Alexey Makarov,Mangesh Sadashiv Bordawekar

申请号：

US14273874

公开号：

US20150320749A1

申请日:

2014.05.09

申请国别(地区):

US

年份:

2015

代理人:

摘要：

A solid dosage form of nilotinib is disclosed that comprises: (i) a core comprising 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1 H-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide or a pharmaceutically acceptable salt thereof and excipients and (ii) at least one polymer, said polymer coating said core, wherein disintegration of said solid dosage form is delayed

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