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Optycznie aktywny cykliczny alkohol i sposób jego wytwarzania
专利权人:
Mitsubishi Tanabe Pharma Corporation
发明人:
OKAMOTO, MASAKI,SAKURAGI, AKIRA,MORI, YOSHIKAZU,KISHIDA, MUNEKI,TAKANORI, HIGASHIJIMA
申请号:
PL11005071
公开号:
PL2371820T3
申请日:
2006.10.04
申请国别(地区):
PL
年份:
2014
代理人:
摘要:
The present invention relates to a method for preparing an optically active cyclic alcohol compound represented by general formula [I]: [wherein R represents a hydrogen atom or a protecting group for amino group, and * represents an asymmetric carbon atom.] which comprises a step of subjecting a cyclic ketone compound represented by general formula [II]: [wherein R has the same meaning as defined above.] to asymmetric reduction (A) in the presence of an optically active oxazaborolidine compound and a boron hydride compound, or (B) in the presence of an asymmetric transition metal complex obtained from a transition metal compound and an asymmetric ligand and a hydrogen donor, and relates to said compound.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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