A compound (1): X can be or s； X rsqoe； can be or s； can be NH Or absent； R1 is selected from arilo, heterosexual, C1-6 arilalquilo, C1-6 heterosexual and a set of formulas (a) or (b),donde R3 y R4 son iguales o diferentes y pueden ser en forma independiente H o se seleccionan entre el grupo que consiste en cicloalquilo C3-8 arilo arilalquilo C1-6 heteroarilo y heteroarilalquilo C1-6 que pueden estar opcionalmente sustituidos con uno oms sustituyentes seleccionados entre -Sh-no2-cn-conh2-cooh, alcoxicarbolinio C1-6, alcoulfanilo C1-6, alcoilsulfinio C1-6 and C1-6 tar. If R3 and R4 are in separate arilo or heterogeneous form, they can be combined with r = 0-2 through an R (CH2) r to form a three ring system. Any group of them can form a three ring system Methyl alkene (CH2) r can be replaced by a heteroatom or heteroaromatic group selected from O, s, N and NH, provided that R3 and R4 are not the same h； R2 is a formula group (c) or (d),Where M = 1, 2 or 3； n = 1, 2 or 3； a = physiologically acceptable anion； R5 is a set of formulas: - (CH2) P - (CH2) P - (CH2) Q -, W, where p is an integer between 0 or 1 to 4； q is an integer between 0 or 1 to 4； P is not or from - O -.- yes.-S (O) --S (O2) --C (O) --CO (O) --N (R6) --CH=CH---N (R6) (SO2) --N (R6) CO (O) --N (R6) C (O) --SO2N (R6) --CO (O) N (R6) - y -C (O) N (R6) -W is selected from a group consisting of H, C1-6 tar, c2-6 alquenilo c2-6, C3-8 cyclopropyl compound, C3-8 isopropyl compound, arilo and isopropyl compound, and can optionally be replaced by an alternative selected from one or more halogen atomic groups.-SH, -NO2, -N (R6) 2, -CN, -CON (R6) 2, -COOH, -NHCOR6, -CO2R6, C1-6 alkoxycarbonyl, C1-6 alkylsulfanyl, C1-6 alkylsulfinyl, C1- alkylsulfonyl 6, C1-6alkyl, C1-6alkoxy, aryl, and heteroaryl； R6 is, independently at each occurrence, H or is selected from the group consisting of C1-6 alkyl, C1-6 haloalkyl, C2-6 alkynyl, C2-6 alkenyl, C3-8 cycloalkyl, aryl heteroaryl, optionally substituted with one or more s
