THOMAS BUTLER,AESOP CHO,CHOUNG U. KIM,OLIVER L. SAUNDERS,LIJUN ZHANG,JAY PARRISH
申请号:
HK11106883.4
公开号:
HK1152709B
申请日:
2011.07.05
申请国别(地区):
HK
年份:
2015
代理人:
摘要:
Provided are pyrrolo[1,2-f][1,2,4]triazinyl, imidazo[1,5-f][1,2,4]triazinyl, imidazo[1,2-f][1,2,4]triazinyl, and [1,2,4]triazolo[4,3-f][1,2,4]triazinyl nucleosides, nucleoside phosphates and prodrugs thereof, wherein the 1' position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.