Thomas BUTLER,Aesop CHO,Choung U. KIM,Jay P. PARRISH,Oliver L. SAUNDERS,Lijun ZHANG
申请号：
US13649511
公开号：
US20130344028A2
申请日:
2012.10.11
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided are pyrrolo[1,2-f][1,2,4]triazinyl, imidazo[1,5-f][1,2,4]triazinyl, imidazo[1,2-f][1,2,4]triazinyl, and [1,2,4]triazolo[4,3-f][1,2,4]triazinyl nucleosides, nucleoside phosphates and prodrugs thereof, wherein the 1′ position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.
