NOUVEL ANTICORPS MONOCLONAL ANTI-EGFR, PROCÉDÉ DE PRODUCTION ET SON UTILISATION

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专利权人:

Ltd;Shanghai Biomabs Pharmaceuticals Co.

发明人:

QIAN, Weizhu

申请号：

EP16734886

公开号：

EP3242895A4

申请日:

2016.01.04

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention provides a method for producing an anti-EGFR monoclonal antibody and the applications thereof. The method comprises the steps of: designing and synthesizing the light chain and heavy chain according to the codons preferred by Chinese hamster, transfecting GS knockout host cells CHO-CR-GS−/−, culturing cells using serum-free technology, isolating and purifying the antibody, and obtaining the low immunogenicity CMAB009 antibody.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/