NOUVEL ANTICORPS MONOCLONAL ANTI-EGFR, PROCEDE DE PRODUCTION ET SON UTILISATION

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专利权人:

LTD;SHANGHAI BIOMABS PHARMACEUTICALS CO.

发明人:

QIAN, WEIZHU

申请号：

CA2973163

公开号：

CA2973163A1

申请日:

2016.01.04

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present invention provides a method for producing an anti-EGFR monoclonalantibody and the applicationsthereof. The method comprises the steps of: designing and synthesizing thelight chain and heavy chain according to the codonspreferred by Chinese hamster, transfecting GS knockout host cells CHO-CR-GS-/-, culturing cells using serum-free technology,isolating and purifying the antibody, and obtaining the low immunogenicityCMAB009 antibody.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/