Yanwen Jin;David Weaver;Michael Rynkiewicz;Cheng Cao
发明人:
Yanwen Jin,David Weaver,Michael Rynkiewicz,Cheng Cao
申请号：
US13982173
公开号：
US09028832B2
申请日:
2011.03.25
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A humanized anti-EGFR antibody L4-H3 and gene encoding the antibody are disclosed. The antibody is composed of a heavy chain and a light chain. The amino acid sequence of the heavy chain variable region is shown as positions 1-145 of SEQ ID NO: 3, the heavy chain constant region is the heavy chain constant region of the human antibody IgG1, and the amino acid sequence of the light chain is shown as SEQ ID NO: 1.
