PROBLEM TO BE SOLVED: To provide: an absorbing gelatin particle which is comprised of nonporous-solid spherical gelatin having a specific jelly strength a gelatin particle having this gelatin particle in which bioactive substance is dissolved and retained and a device for a use in which the bioactive substance dissolved, absorbed and retained in the gelatin particle is distributed in an injector together with saline solution.SOLUTION: The absorbing gelatin particle comprises gelatin having of the jelly strength of 80 to 120 g, in which solid spherical gelatin is crosslinked with heat and the absorbing gelatin particle has the particle diameter of 50 to 2000 μm. In particular, the invention is available as a device for: blood vessel embolization sustained-release of bioactive substance in which bioactive substance is dissolved and retained administration into a living body by the way where the gelatin particle for sustained-release of a bioactive substance is distributed together with saline solution in an injector and the injector is filled up with it.COPYRIGHT: (C)2014,JPO&INPIT【課題】 本発明は多孔質でない中実球状で特定のゼリー強度のゼラチンからなる膨潤ゼラチン粒子、およびこのゼラチン粒子に生理活性物質を溶解保持してなるゼラチン粒子、ならびに注射器内に生理食塩水と共に生理活性物質を溶解含浸保持したゼラチン粒子を分散させて使用するデバイスを提供するものである。【解決手段】 ゼリー強度が80~120gのゼラチンからなり、熱架橋された中実球状の膨潤ゼラチン粒子であって、膨潤ゼラチン粒子の粒径が50~2000μmであることを特徴とする。特に、血管塞栓用途や、生理活性物質を溶解、保持して生理活性物質を徐放する用途や、注射器内に生理食塩水と共に生理活性物質徐放用ゼラチン粒子を分散、充填して体内投与用のデバイスとして用いることができる。【選択図】 なし
