DOTSON JENNAFER,HEFFRON TIM,OLIVERO ALAN G,SUTHERLIN DANIEL P,STABEN STEVEN,WANG SHUMEI,ZHU BING YAN,CHUCKOWREE IRINA S,FOLKES ADRIAN J,WAN NAN CHI
申请号：
IN2843/DELNP/2011
公开号：
IN2011DN02843A
申请日:
2011.04.18
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
Compounds of Formula I, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including p110 alpha and other isoforms of PI3K, and for treating disorders such as cancer or inflammation mediated by lipid kinases. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
