A method of manufacturing extract capable of absorbing harmful metal inside body comprises: first providing natural vegetables and fruits and extracting B-M thiopeptide from the natural vegetables and fruits at the same time, placing the natural vegetables and fruits in a fermentation tank to extract mixed nutrients from the natural vegetables and fruits and finally mixing the B-M thiopeptide and mixed nutrients in a predetermined drink. Thus, when the extract enters a human body, it will gradually release the B-M thiopeptide for capturing and combined with heavy metals, followed by being re-absorbed in the human body to retain substances beneficial to human body and expelling the accumulated metal harmful to the body to repair the metabolism functionality of the human body.