The Florey Institute of Neuroscience and Mental Health
发明人:
BATHGATE, Ross Alexander David,HOSSAIN, Mohammed Akhter,WADE, John Desmond
申请号:
EP15780000
公开号:
EP3131925A4
申请日:
2015.04.17
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Provided herein are biologically active single chain relaxin peptides. In particular the present invention relates to single chain relaxin peptides comprising a B chain derived from relaxin-2, the peptide being truncated by one or more amino acid residues at the N-terminus with respect to the sequence of the B chain of native relaxin-2. Typically the single chain relaxin peptides selectively bind to the RXFP1 receptor.