The present disclosure relates to the field of food and/or drug technology. Disclosed is a blood lipid-lowering composition, method for preparing the same and use thereof. The blood lipid-lowering composition comprises echium seed oil, camelina seed oil and safflower seed oil. The specific natural substances echium seed oil, camelina seed oil and safflower seed oil are used as the functional ingredients to form a natural composition that can significantly reduce the total cholesterol and triglyceride levels and increase the content of the serum apolipoprotein A1, having an obvious blood lipid-lowering function, which may be used in developing and preparing blood lipid-lowering drugs and foods, especially health care foods.本發明涉及食品和/或藥品技術領域，公開了一種降血脂組合物及其製備方法和應用。本發明所述降血脂組合物包括藍薊籽油、薺藍籽油和紅花籽油。本發明以特定的天然物質藍薊籽油、薺藍籽油以及紅花籽油作為功效成分，組成一種可顯著降低總膽固醇和甘油三酯以及提高血清載脂蛋白A1含量的天然組合物，具備明顯的降血脂功效，可應用於降血脂藥品和食品，特別是保健食品的開發製備中。
